Eltrombopag (Revolade) 25mg: Uses, Dosage, Side Effects and Safety Information

Eltrombopag helps raise low platelet counts in certain blood conditions. This Eltrombopag low platelet guide explains how it is taken, including important food and mineral-timing rules.
What Is It?
Eltrombopag is a thrombopoietin receptor agonist, a medicine that stimulates the bone marrow to produce more platelets, used for chronic immune thrombocytopenia (ITP), certain hepatitis C-related low platelet counts, and some cases of aplastic anaemia.
How Does It Work?
It mimics the action of thrombopoietin, the body’s natural hormone that signals bone marrow to produce platelets, helping raise platelet counts in conditions where they are dangerously low.
Who Is It Prescribed For?
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Adults and some children with chronic ITP who haven’t responded well to other treatments, prescribed by a haematologist.
Dosage and How to Take It
Usually taken once daily on an empty stomach, at least one hour before or two hours after eating. Your haematologist sets your starting dose and adjusts it based on regular platelet count monitoring.
What If I Miss a Dose?
If a dose is missed, take it as soon as remembered that day if a full 12 hours or more remain before the next scheduled dose; otherwise skip it and resume the next day.
Common Side Effects
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Headache
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Nausea
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Diarrhoea
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Upper respiratory infections
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Fatigue
Serious Side Effects, Seek Help If You Notice:
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Signs of liver problems: yellowing skin or eyes, dark urine
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Signs of a blood clot: swelling, pain, or redness in a limb, sudden chest pain or breathlessness
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Platelet counts rising too high (monitored by blood tests)
Warnings and Precautions
As noted in this Eltrombopag low platelet guide, liver function is checked regularly during treatment. Because eltrombopag raises platelet counts, blood clot risk is monitored, particularly in people with other clotting risk factors. Platelet counts are checked frequently to fine-tune the dose and avoid overshooting.
Drug and Food Interactions
Avoid taking within four hours of antacids, calcium, iron, zinc, or other mineral supplements and many dairy products, as these bind to eltrombopag and significantly reduce how much is absorbed.
Storage
Store below 30°C in the original container, away from direct sunlight and moisture. Keep out of reach of children.
Frequently Asked Questions
Why can’t I take this with my calcium or iron tablets? Minerals like calcium, iron, and zinc bind to eltrombopag in the gut and prevent it from being absorbed properly, so a several-hour gap is needed.
How often will my platelet count be checked? Typically weekly at first, then less often once your dose is stable, as directed by your haematologist.
Got a prescription ?
You can get Eltrombopag (Revolade) 25mg on HubPharm (PCN LAG20247B39C9)
This article is reviewed by Pharmacist Sesan Kareem, B.Pharm, MPA, MBA and is for educational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always take medicines exactly as prescribed by your doctor. Chat with a HubPharm pharmacist on WhatsApp with any questions before starting, stopping, or changing a medicine.



