This Enzalutamide 160mg prostate cancer guide explains how this oral hormone therapy works in advanced prostate cancer, how it is taken, and what patients and caregivers should watch for during treatment.
What Is It?
Enzalutamide is an androgen receptor inhibitor, a targeted oral therapy that blocks the effect of testosterone-driven signals on prostate cancer cells, including in castration-resistant disease that has stopped responding to standard hormone therapy.
How Does It Work?
It binds directly to the androgen receptor on cancer cells, preventing testosterone from activating genes that drive tumor growth, slowing disease progression even when testosterone levels in the blood are already low.
Who Is It Prescribed For?
Adults with metastatic or non-metastatic castration-resistant prostate cancer, prescribed by an oncologist or urologist.
Dosage and How to Take It
The standard total daily dose is 160mg, taken once daily at approximately the same time, with or without food. Capsules or tablets are swallowed whole. Treatment continues as long as it remains effective and tolerable, as determined by regular oncology review.
What If I Miss a Dose?
If a dose is missed, take it as soon as remembered the same day; if a full day is missed, resume the normal schedule the next day without doubling up.
Common Side Effects
Fatigue
Hot flashes
Joint or muscle pain
High blood pressure
Reduced appetite
Serious Side Effects, Seek Help If You Notice:
Seizures (a known but uncommon risk with this drug class)
Falls or fractures related to dizziness or muscle weakness
Signs of heart problems such as chest pain or irregular heartbeat
Severe skin reactions
Warnings and Precautions
According to this Enzalutamide 160mg prostate cancer guide, enzalutamide carries a small risk of seizures; patients should not drive if they experience seizure warning signs and should inform their doctor of any history of seizures or brain conditions before starting. It is not for use in women. Blood pressure should be monitored regularly during treatment.
Drug and Food Interactions
Enzalutamide interacts with a wide range of other medicines, including some blood thinners, statins, and antidepressants, because it strongly affects how the liver processes drugs. Always give your pharmacist your full medicine list before starting.
Storage
Store below 30°C in a cool, dry place, away from direct sunlight. Keep out of reach of children.
Frequently Asked Questions
Can enzalutamide be taken alongside other prostate cancer treatments? It is often used alongside ongoing hormone (androgen deprivation) therapy; your oncologist will confirm your full treatment plan.
What should I do if I feel unusually dizzy or have a seizure warning sign? Stop what you are doing, avoid driving, and contact your oncology team or seek urgent medical care immediately.
This article is reviewed by Pharmacist Sesan Kareem, B.Pharm, MPA, MBA and is for educational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always take medicines exactly as prescribed by your doctor. Chat with a HubPharm pharmacist on WhatsApp with any questions before starting, stopping, or changing a medicine.
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