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Mpox Symptoms and Prevention: A Clear Guide

Diagram of mpox rash stages from spots to scabs, with mpox symptoms and prevention steps
Written byMuiz Adeyemi EshinlokunFrontend Engineer and Content Lead, Computer Science (ND, HND)
Medically reviewed byPharm. Sesan Kareem, B.Pharm, MPA, MBAReviewed 9 November 2026PCN Reg. 019784
Last updated 9 November 2026How we write and check this information

Mpox, formerly known as monkeypox, is a viral infection that has been reported in Nigeria for many years. Since 2017, cases have been recorded across many states, and the disease has gained global attention through international outbreaks. Most people recover, but mpox can be serious, especially for young children, pregnant women and people with weakened immunity. This guide explains mpox symptoms and prevention, and when to seek care.

What mpox is

Mpox is caused by the mpox virus, which belongs to the same family as the virus that once caused smallpox. However, mpox is usually much milder than smallpox. There are different types, called clades, which vary in how severe and how easily spread they are.

How mpox spreads

According to the World Health Organization, mpox spreads mainly through close contact with someone who has mpox. This includes:

  • Skin-to-skin contact, including during sex
  • Touching sores, scabs or body fluids
  • Face-to-face contact, through respiratory droplets
  • Contact with contaminated bedding, towels or clothing
  • From mother to baby during pregnancy or birth
  • Contact with infected animals, such as rodents and monkeys, through bites, scratches or handling bush meat

Early symptoms

Symptoms usually start within one to three weeks of exposure. Early symptoms can include:

  • Fever
  • Headache
  • Muscle aches and back pain
  • Tiredness
  • Swollen lymph nodes in the neck, armpits or groin

Swollen lymph nodes help distinguish mpox from chickenpox.

The mpox rash

A rash usually appears within a few days of the fever, though in some people it is the first sign. It can affect the face, palms, soles, mouth, genitals and anus. The rash passes through stages:

  • Flat spots
  • Raised bumps
  • Fluid-filled blisters
  • Pus-filled sores
  • Crusts or scabs, which fall off

The rash can be painful or itchy. A person remains infectious until all scabs have fallen off and new skin has formed underneath.

Mpox and genital sores

In recent outbreaks, many people have had sores only around the genitals or anus. These can be mistaken for other sexually transmitted infections, such as herpes or syphilis. Anyone with new genital sores should be tested.

Mpox symptoms and prevention in children

Children can catch mpox through close contact with infected family members. They may have more widespread rash and are at higher risk of complications such as dehydration and skin infections. Keep children away from anyone with an unexplained rash. If a child develops fever and a rash, see a health worker. Keep their nails short to reduce scratching, and keep sores clean.

Who is at higher risk of severe illness?

Most people recover within two to four weeks. However, severe illness is more likely in:

  • Young children
  • Pregnant women
  • People living with HIV whose infection is not controlled
  • People with other conditions that weaken the immune system

Complications can include skin infections, pneumonia, eye infections and, rarely, brain inflammation.

Testing and diagnosis

If mpox is suspected, a health worker will take a swab from a sore and send it to a laboratory. Nigeria has testing capacity through public health laboratories. Report suspected cases to your nearest health facility, which will notify the local surveillance team.

Mpox and people living with HIV

People living with HIV whose virus is not well controlled can develop severe mpox. Taking HIV treatment every day and keeping the viral load undetectable protects against severe illness. Anyone diagnosed with mpox should be offered an HIV test. Good HIV care is an important part of mpox symptoms and prevention.

Treatment and care

Most people with mpox need supportive care:

  • Pain relief and fever control  1  with paracetamol
  • Keeping sores clean and dry, and not scratching
  • Saltwater rinses for mouth sores
  • Plenty of fluids and good nutrition
  • Treating any bacterial skin infection with antibiotics if needed

Antiviral medicines are sometimes used in severe cases under specialist care.

HUBPHARM PHARMACIST’S NOTE
Mpox sores can be very painful, especially in the mouth and genital area, and scratching invites infection. Message a HubPharm pharmacist for a discreet home-care pack with pain relief, saltwater rinse guidance and non-stick dressings, delivered without anyone needing to visit a shop. Everything you tell us stays confidential.

Isolation at home

If you have mpox, stay at home in a separate room if possible until all sores have healed. Cover sores  2  with clothing or bandages. Wear a mask around others. Do not share bedding, towels, clothing or utensils. Wash your hands often. Avoid sex until fully healed.

Home isolation steps from mpox symptoms and prevention guidance

Follow your health worker’s advice on how long to isolate.

Mpox symptoms and prevention: protecting yourself

Practical prevention steps include:

  • Avoiding close contact with anyone who has a rash or confirmed mpox
  • Not sharing bedding, towels or clothing with a sick person
  • Washing hands often with soap and water
  • Using gloves when caring for someone with mpox
  • Avoiding contact with wild animals and cooking bush meat thoroughly
  • Practising safer sex and knowing your partners’ health

Learn more about safer sex in our article on condoms and sexual health.

Mpox symptoms and prevention in households

If someone at home has mpox:

  • Keep them in a separate room if possible
  • Wash their bedding and clothes separately in hot water with detergent
  • Clean surfaces they touch with household disinfectant
  • Do not shake bedding, which can spread virus particles
  • Wear gloves and a mask when helping with sores
  • Wash hands often

These steps protect other family members while the person recovers.

Mpox and pregnancy

Mpox in pregnancy can be serious and may affect the baby. Pregnant women should avoid close contact with anyone who has an unexplained rash or confirmed mpox. A pregnant woman who develops fever and a rash should seek care quickly. Health workers will provide close monitoring.

Mpox and stigma

Stigma makes people hide symptoms and delay care. Mpox can affect anyone, regardless of age, gender or sexual orientation. Treating people with respect encourages them to come forward for testing and isolation. Accurate information about mpox symptoms and prevention is more effective than blame.

Caring for your skin during recovery

Keep healing skin clean and moisturised. Avoid picking scabs. Use loose cotton clothing. Seek care if sores become red, hot, swollen or filled with pus, which may signal a bacterial infection.

When to return to normal activities

You can usually return to work, school and normal activities once all scabs have fallen off and a fresh layer of skin has formed. This often takes two to four weeks. Ask your health worker before returning, especially if you work with young children or in health care. Using condoms for some weeks after recovery may be advised. Following these steps completes the cycle of mpox symptoms and prevention.

Reporting and contact tracing

When a case is confirmed, health workers may contact people who were in close contact. They will ask contacts to watch for symptoms for 21 days. This helps stop the spread. Cooperating with contact tracers, and being honest about contacts, protects your community.

Vaccines for mpox

Vaccines that protect against mpox exist. They are mainly offered to people at high risk, such as health workers and close contacts of cases, during outbreaks. Availability in Nigeria depends on national programmes.

Myths about mpox

“Mpox only affects certain groups.” Anyone can get mpox through close contact.

“Mpox is the same as chickenpox.” They are different viruses. Swollen lymph nodes are more typical of mpox.

“Mpox always kills.” Most people recover, but some groups are at higher risk.

Advice for health workers

Health workers caring for people with mpox should use gloves, gowns, masks and eye protection. Handle bedding and dressings carefully. Report suspected cases to the local disease surveillance officer. Clear guidance on mpox symptoms and prevention protects staff and patients.

Getting help

Knowing mpox symptoms and prevention helps protect you and those around you. If you develop an unexplained rash, especially with fever or swollen glands, see a health worker and avoid close contact with others. For pain relief, wound care supplies or advice on isolation at home, message a HubPharm pharmacist or chat with Afiya on WhatsApp.

Medicines and products in this article

# Medicine or product What to know
1 Paracetamol

Over the counter

For pain and fever during mpox.
2 Non-stick wound dressings

Over the counter

Cover sores to reduce spread and protect healing skin.

 

To order any of these, or to ask a pharmacist a question first, message HubPharm on WhatsApp or visit hubpharmafrica.com. Prescription medicines are supplied against a valid prescription.

References

  • Centers for Disease Control and Prevention. Mpox.

 

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